Type 2 diabetes: A life-threatening metabolic disease.
Type 2 diabetes is a disease in which the body has difficulty controlling blood sugar and using it for energy, causing serious health problems. These problems can include chronic inflammation, weight gain, cardiovascular disease, and stroke. Insulin, an important hormone produced in the pancreas, plays a key role in regulating glucose. Maintaining healthy glucose levels is an important goal of long-term diabetes therapy.
Limitations of type 2 diabetes drugs.
Progressive disease
There are no drugs approved for type 2 diabetes today that can halt the progressive nature of the condition.
Lifelong therapy
All drugs used for type 2 diabetes, even newer drugs like GLP-1s, often must be taken for the rest of a person’s life to control symptoms of the disease.1
Side effects
People taking type 2 diabetes drugs may experience undesirable side effects, like nausea and vomiting, and insulin therapy can cause weight gain and risk of very low blood sugar levels.2, 3
The important role of the pancreas in type 2 diabetes.
The pancreas is an important organ for maintaining metabolic health. In it, clusters of cells called “pancreatic islets” produce a key hormone called insulin, which plays a crucial role in endocrine function and glucose control. When beta cells are damaged by the chronic, toxic effects of obesity, the loss of insulin production and secretion can result in the development of type 2 diabetes.
Exploring new approaches to type 2 diabetes.
Revita
An outpatient endoscopic procedure designed to resurface the lining of the duodenum—targeting a root cause of obesity and type 2 diabetes.
Rejuva
A one-time gene therapy platform designed to enable the long-term remission of obesity and type 2 diabetes by targeting pancreatic islet cells.
Now recruiting for a clinical research study in type 2 diabetes.
- Type 2 diabetes – Understanding medicine. NHS. https://www.nhs.uk/conditions/type-2-diabetes/understanding-medication/
- Diabetes treatment: Medications for type 2 diabetes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/in-depth/diabetes-treatment/art-20051004
- Side effects of insulin. Diabetes UK. https://www.diabetes.org.uk/guide-to-diabetes/managing-your-diabetes/treating-your-diabetes/insulin/side-effects
Revita® is for investigational use only in the US under Federal law. We hereby disclaim any warranties or guarantees regarding the efficacy or safety of Revita®. While we strive for quality and reliability, individual results may vary. Users are encouraged to consult with healthcare professionals and assess personal suitability before using the device.
Rejuva® is in early development and not approved by any regulatory body for investigational or commercial use.